Abu Hafs al Shahri, was the target of the drone strike which occurred within the last few days, two US officials said on Thursday.
"We have no knowledge of that," said Pakistan military spokesman Major Gen. Athar Abbas.
"We have neither heard of this man operating in this region, nor can we confirm his death," said one.
Taliban militants were not immediately available for comments.
As al Qaeda's Pakistan operations chief, one of the US officials said, al Shahri's responsibilities included coordinating the activities of al Qaeda's depleted central leadership with network of Taliban militants, known as the TTP.
Copyright Reuters, 2011