The win in Florida for Trump sent rival Marco Rubio, the US senator from the Sunshine State, crashing out of the campaign. The 69-year-old billionaire also won in Illinois and North Carolina.
Clinton was victorious in Florida, Ohio, Illinois and North Carolina, while Ohio's Republican Governor John Kasich won in his home state.
The contest in Missouri was still too close to call.
Here is a state-by-state breakdown of winners in Tuesday's contests, according to US network projections:
Florida
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Republican: Donald Trump
Democratic: Hillary Clinton
Illinois
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Republican: Donald Trump
Democratic: Hillary Clinton
Missouri
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Republican: unknown
Democratic: unknown
North Carolina
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Republican: Donald Trump
Democratic: Hillary Clinton
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Republican: John Kasich
Democratic: Hillary Clinton
- TOTAL WINS -
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Democrats:
Hillary Clinton: 4
Bernie Sanders: 0
Republicans:
Donald Trump: 3
John Kasich: 1
Ted Cruz: 0
Marco Rubio: 0
