The Hang Seng Index fell 0.33 percent, or 76.26 points, to 22,860.96.
The benchmark Shanghai Composite Index lost 0.63 percent, or 19.73 points, to 3,088.37 and the Shenzhen Composite Index, which tracks stocks on China's second exchange, dropped 0.74 percent, or 15.21 points, to 2,029.49.