HEALTH UPDATE: pineapple crush can fight cancer

11 Jul, 2005

Australian scientists have discovered pineapple molecules can act as powerful anti-cancer agents and said Thursday (July 7) the research could lead to a new class of cancer-fighting drugs. Scientists at the Queensland Institute of Medical Research (QIMR) said their work centred on two molecules from bromelaine, an extract derived from crushed pineapple stems that is used to tenderise meat, clarify beers and tan hides.
One of the molecules, CCZ, stimulates the body's immune system to target and kill cancer cells, the other, CCS, blocks a protein called Ras, which is defective in 30 percent of all cancers.
QIMR researcher Tracey Mynott said her team had set out to find why the enzyme-rich bromelaine crush had such strong effects on biological material.
"In searching for these components, we discovered the CCS and CCZ proteins and found that they could block growth of a broad range of tumour cells, including breast, lung, colon, ovarian and melanoma," Mynott said in a statement.

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