Application of large amounts of skin-numbing lotions, creams and gels that are widely used in cosmetic and medical procedures can cause dangerous side effects such as irregular heart rhythm and seizures.
Two deaths have been linked to application of large amounts of these topical anesthetics in USA, CBC News reported quoting a warning by the US Food and Drug Administration (FDA).
Two women, aged 22 and 25, died after using the products on their legs after laser hair removal.
The FDA said the women "wrapped their legs in plastic wrap, as they were instructed, to increase the creams' numbing effect. Both women had seizures, fell into comas, and subsequently died from the toxic effects of the anesthetic drugs." The agency also said that it's received reports of side effects such as irregular heartbeats and slowing or stopping of breathing in people who've used the topical anesthetics.