Fatty acids in diet affect ulcerative colitis risk

14 Dec, 2009

People who eat lots of red meat, cook with certain types of oil, and use some kinds of polyunsaturated fatty acid (PUFA)-heavy margarines may be increasing their risk of a painful inflammatory bowel disease, a study in more than 200,000 Europeans shows.
These foods are high in linoleic acid and the study have found that people who were the heaviest consumers of this omega-6 PUFA were more than twice as likely to develop ulcerative colitis as those who consumed the least.
Dr Andrew Hart of the University of East Anglia in Norwich, UK, and his colleagues also found that eating more eicosapentaenoic acid, an omega-3 fatty acid found in fish and fish oils, was associated with a lower risk of the disease.
While people need a certain amount of linoleic acid to survive, Hart noted in an interview with Reuters Health, excess amounts are taken up into the lining of the colon, and if they're released, they can promote inflammation.

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