Zinedine Zidane's men will travel to Cyprus to take on Apoel without their captain Sergio Ramos, who ruled out from the clash due to broken nose.
The center back from Spain got the knock on his nose during Madrid derby at Wonder Metropolitano on Saturday.
Off the back of a heavy defeat to Tottenham at Wembley, the Spanish giants will look for a win to see them through to the next stage of Europe's elite competition.
After two impressive draws against Borussia Dortmund, Apoel will be hoping they can clinch a spot in the Europa League. They'll need Spurs to take all three points off Dortmund to keep their European dream alive.
This match will take place on November 21 at the GSP Stadium in the Cypriot capital, Nicosia.
Madrid’s 20-member squad is as under:
📋 Estos son los 20 convocados para el partido contra el @apoelfcofficial. 👇#RMUCL | #HalaMadrid pic.twitter.com/lRPegobtf8
— Real Madrid C.F. (@realmadrid) November 20, 2017