GENEVA: The World Health Organization said Wednesday that healthcare facilities and personnel globally were being attacked at an unprecedented rate -- in particular in the conflict in Ukraine.

"We've never seen globally... this rate of attacks on healthcare," the WHO's emergencies director Michael Ryan told reporters.

"Health is becoming a target," he lamented. "It is becoming part of the strategy and tactics of war."

Attacks on healthcare have been rising around the world, with 89 registered globally since the start of the year -- but nowhere has the pace of attacks been faster than in war-ravaged Ukraine.

In just the three weeks since Russia launched its full-scale invasion on February 24, there have been at least 43 attacks on healthcare in Ukraine, according to a WHO tally.

The verified attacks, which have killed 12 people and injured 34, include 34 attacks on hospitals and other health facilities, seven on ambulances and 10 on health personnel, WHO said.

In one of the most shocking instances, a maternity and children's hospital in the southern city of Mariupol was shelled last week, killing three people, including a child.

At least three people were killed, including a young girl, in an attack Wednesday on a children's hospital in Mariupol in southern Ukraine.

Moscow and Kyiv see signs of compromise on Ukraine's security status

"This crisis is reaching a point where the health system in Ukraine is teetering on the brink," Ryan said, warning that the attacks were also making it far more difficult for WHO to send in support.

"How can we put emergency medical teams on the ground if the very facilities that they may want to go and support are going to be attacked, and going to be bombed and going to suffer catastrophic damage?"

Ryan stressed that international humanitarian law requires those fighting not only to not target health facilities, but to "specifically take measures to avoid attacking or inadvertently destroying" them.

Destroying health facilities, he said, was "not just about the destruction of buildings."

"This is about the destruction of hope. This is about taking away the very thing that gives people the reason to live: the fact that their families can be taken care of, that they can be cured if they're sick, that they can be treated if they're injured."

WHO chief Tedros Adhanom Ghebreyesus agreed.

"Attacks on healthcare not only endanger lives, they deprive people of urgently-needed care and break already-strained health systems," he told reporters.

WHO said 300 health facilities are along the conflict front lines in Ukraine, or in areas now under Russian control.

Another 600 facilities are within 10 kilometres of the conflict line.