In Britain, a battle to spin great science into gold

24 May, 2014

It's mega strong, ultra light and super stretchy, and if things work out, a wonder material discovered in Britain could change many aspects of human existence - starting with peoples' sex lives. Safer and sensually superior condoms may not have been the first thing on the minds of the Nobel-winning team at the University of Manchester that isolated graphene a decade ago, but they may be an early eye-catching use of the new one-atom-thick material.
Billed as potentially the most important discovery of this century, graphene - the thinnest material on earth and 200 times stronger than steel - is also exciting researchers around the world exploring its use in everything from electronics to nanotech drug delivery. For British science, among the biggest questions is whether graphene's home nation can spin its breakthrough into real monetary gain, or whether - as a Thomson Reuters patent analysis suggests - global big hitters will nip in and grab the market.
A new government-backed $100 million National Graphene Institute opens next year in Manchester aimed at putting Britain at the heart of a much hoped-for graphene revolution.
"Manchester is not unique in terms of graphene research, but if we start to create this cluster, it could become unique." Yet a Thomson Reuters analysis of world-wide patent filings shows graphene's birthplace is already falling behind, with China and the United States leading the pack when it comes to finding ways to exploit this previously unknown form of carbon.
The organisation with the most patent filings is South Korean consumer electronics giant Samsung Electronics, eyeing graphene's potential in flexible touchscreen displays and other areas. The story shows the problems facing a mid-sized economy like Britain, with a limited industrial base, striving to monetize its science in an increasingly globalized world.
Britain's $2.5 trillion economy may still retain a leading position in certain high-tech fields like aerospace and pharmaceuticals but the competition is intense and cross-border corporate deals can change the landscape overnight.
"I'm confident because I'm a 'glass half full' person, but it's not an easy sell," he said. "We need some big British companies to be prepared to back the vision with some serious engagement, resources and funding."
Britain has been here before. Forty years ago, two researchers at the Laboratory of Molecular Biology in Cambridge, England, discovered a way to produce highly specific antibodies - the foot soldiers of the immune system - in a test tube. Cesar Milstein and Georges Koehler thought their process might one day have a commercial application but the government department backing them did not seek a patent when their work on monoclonal antibodies was published in 1975.
Today, the world is awash with monoclonal antibody patents and six of the 10 top-selling medicines in the world are made from them - but none are sold by British firms. British scientists also did much of the work that led to liquid crystal displays, used in flat-screen computers and televisions, as well as studying the potential of carbon fiber. In these cases, too, it was foreign companies that profited.
And with penicillin, one of the greatest medical discoveries of the last century - by Alexander Fleming in Britain in 1928 - it was scientists working for Pfizer who developed a deep-tank fermentation method that enabled mass production of the drug for use in World War Two. "Time after time, Britain has led the way in scientific research - only to see the commercial benefits accrue overseas," finance minister George Osborne told a gathering of scientists in Cambridge last month.
Certainly, the country has a scientific record to be proud of, with three of the world's top universities in Oxford, Cambridge and Imperial College London, as well as a run rate of at least one Nobel prize a year since 2009. Yet the country files fewer patents each year than the United States, Japan, Germany, France, China and South Korea, and even in its chosen field of graphene it comes in seventh place.
In the labs at the University of Manchester, Aravind Vijayaraghavan, who leads graphene research here, says his team is bent on making the kind of fundamental breakthroughs that will convince big British business to back the wonder material. Graphene could be used for everything from flexible foldable mobile phones and tablet computers, to ultra-light aircraft wings, to life-saving water filtration systems, to targeted cancer therapies.
The idea is that the next-generation contraceptive would be made from a composite material "tailored to enhance the natural sensation during intercourse", he said, combining the strength of graphene with the elasticity of latex. "We want to produce a new material which can be thinner, stronger, more stretchy, safer and perhaps most importantly more pleasurable."

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