Disappointing corporate earnings in the European banking sector added to the cautious start to the week's trading.
Chinese state media launched an unusually personal attack against US President Donald Trump's trade policies on Monday, saying Trump's trade "extortion" would not work.
It also sought to reassure investors about Chinese economic strength as the months-long dispute rattles financial markets and raises deepening worries about the impact on the real economy.
After an initial rise, Asian shares earlier succumbed to selling pressure, with Chinese shares sliding into negative territory.
European shares were also mixed. The pan-European share index dropped 0.06 percent while Germany's DAX fell 0.34 percent and France's CAC 40 was virtually flat, down 0.02 percent.
The biggest plunge in German industrial orders in nearly 18-months added to pressure on German stocks.
The weakness in European shares followed a more than 1 percent drop in the Chinese blue-chip index and Shanghai's SSE Composite. Japan's Nikkei and South Korea's Kospi index also dropped.
The MSCI world equity index, which tracks shares in 47 countries edged down 0.08 percent.
"In his latest Twitter tirades and his latest appearances in front of his supporters the US president has indicated something akin to a "strategy" behind his trade war policy," Commerzbank said. "The trade war will remain in place regardless of how much the Chinese cave in."
The trade dispute remains a live issue for markets with China proposing tariffs on $60 billion worth of US goods on Friday, while a senior Chinese diplomat cast doubt on prospects of talks with Washington to resolve the bitter trade conflict.
At the same time, Trump said his strategy of placing steep tariffs on Chinese imports is "working far better than anyone ever anticipated", citing losses in China's stock market. He predicted the US market could "go up dramatically" once trade deals were renegotiated.
The People's Bank of China's intervention last week to impose a reserve requirement on foreign exchange forward contracts had the desired impact of halting the slide in the yuan.
In offshore markets, the Chinese currency fell 0.1 percent against the dollar to 6.8562 on Monday, but was well away from the 6.91 weak point the yuan had plumbed last week.
The yuan has been one of the main casualties from the trade conflict, with many investors speculating that the PBOC was happy for the renminbi to weaken to counter the impact of US tariffs.
Traders saw the PBOC effort as an attempt by Chinese authorities to show they wanted stability, and some interpreted it as a conciliatory move to nudge the Americans towards the negotiating table.
Other said the intervention would not stop further yuan weakness with Washington and Beijing at loggerheads over tariffs.
The dollar index, which has benefited as investors rush to safety, rose 0.2 percent to 95.291, close to a 2-1/2 week high.
US jobs data on Friday, although weaker than expected, underlined that the world's largest economy is growing robustly, supporting synchronized global growth that had underpinned sentiment towards risk assets before the eruption of the trade dispute.
Markets are increasingly nervous about whether US growth may have peaked.
"Investors are also closely watching the rising value of the US dollar, slowing global economic growth and the risk of the Federal Reserve tightening short-term interest rates too quickly and dampening domestic economic growth," said Lachlan McPherson, Senior Investment Consultant at Charles Schwab Australia.
The euro inched down to $1.155.
The British pound slid towards a fresh 10-month low after the UK trade minister warned Britain was headed for a no-deal Brexit.
Brent crude futures rose 0.5 percent to $73.55, while US crude oil futures added 0.7 percent to $68.94 a barrel.