First innings hero Kagiso Rabada struck two early blows as South Africa pushed for victory on the fourth day of the fourth and final Test against England at SuperSport on Monday.
England, set an unlikely target of 382 on a deteriorating pitch, were 52 for three at the close after South Africa declared their second innings on 248 for five.
Rabada, who took seven for 112 in the first innings, dismissed Alex Hales and Nick Compton, while new ball partner Morne Morkel claimed the wicket of England captain Alastair Cook for the second time in the match.
If South Africa are able to take the remaining seven wickets on Tuesday it would be a consolation victory, with England holding a winning 2-0 lead in the series.
Hales made only one run before he received a virtually unplayable ball from Rabada which shot through low and trapped the batsman in front of his stumps.
It finished a disappointing series for Cook's latest opening partner. Hales made 136 runs in eight innings at an average of 17.00.

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South Africa, first innings,              475
England, first innings,                   342
South Africa, second innings (overnight 42-1)
S. Cook c Bairstow b Anderson              25
D. Elgar c Bairstow b Anderson              1
H. Amla c Bairstow b Broad                 96
A. de Villiers lbw b Anderson               0
J. Duminy c Bairstow b Stokes              29
T. Bavuma not out                          78
Q. de Kock not out                          9
Extras: (b2, lb5, w3)                      10
Total: (5 wkts dec, 83.2 overs)           248
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Fall of wickets: 1-5 (Elgar), 2-49 (Cook), 3-49 (De Villiers), 4-106 (Duminy), 5-223 (Amla)
Bowling: Anderson 18-5-47-3, Broad 15-4-33-1 (1w), Stokes 16-4-36-1, Woakes 13.2-0-53-0 (1w), Ali 17-3-60-0, Root 4-0-12-0

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England, second innings
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A. Cook c and b Morkel                      5
A. Hales lbw b Rabada                       1
N. Compton c De Kock b Rabada               6
J. Root not out                            19
J. Taylor not out                          19
Extras: (lb2)                               2
Total: (3 wkts, 21 overs)                  52
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Fall of wickets: 1-2 (Hales), 2-8 (Cook), 3-18 (Compton)
Bowling: Morkel 6-4-12-1, Rabada 6-2-15-2, Abbott 1-0-6-0, Piedt 5-2-7-0, Elgar 2-1-8-0, Duminy 1-0-2-0
Toss: South Africa
Umpires: Kumar Dharmasena (SRI), Chris Gaffaney (NZL)
TV umpire: Rod Tucker (AUS)
Match referee: Ranjan Madugalle (SRI).