A ball-shaped artificial intelligence robot nicknamed the "flying brain" because it is trained to follow and interact with a German astronaut blasted off Friday toward the International Space Station aboard SpaceX's Dragon cargo ship.
A spare hand for the station's robotic arm, an experiment to measure plant stress and a study of a new cancer treatment were also on board as the Falcon 9 rocket lifted off from Cape Canaveral, Florida at 5:42 am (0942 GMT).
"We have ignition and liftoff! The Falcon 9 rocket powers the Dragon spacecraft toward the International Space Station," said a NASA commentator as the white rocket fired its engines and lit up the skies on a dark, Florida morning.
The unmanned Dragon capsule carried 5,900 pounds (2,700 kilograms) on its 15th supply mission to the orbiting lab, as part of a $1.6 billion contract with NASA.
Both the capsule and the rocket have flown before. The Dragon sent cargo to space in 2016 and the Falcon blasted off a NASA satellite two months ago.
The California-based aerospace company headed by Elon Musk is intent on re-using rocket parts and spacecraft to lower the cost of spaceflight.
About 10 minutes into the flight, SpaceX confirmed that the Dragon had successfully deployed from the rocket's second stage and was in a "good orbit."
The capsule is scheduled to reach the station on July 2.
A key piece of cargo is a basketball-sized device called CIMON, or Crew Interactive MObile CompanioN.
It has been described as a "flying brain" by Manfred Jaumann, head of microgravity payloads at Airbus. CIMON's activation will mark "a historical moment," becoming the first robot of its kind to interact with people in space, said Christian Karrasch, CIMON project manager at the German Aerospace Center (DLR), during a NASA press briefing Thursday.