The Hang Seng Index fell 1.0 percent, or 275.39 points, to 28,156.66.
The benchmark Shanghai Composite Index lost 0.25 percent, or 6.91 points, to 2,712.79, while the Shenzhen Composite Index, which tracks stock on China's second exchange, opened 0.20 percent lower, or 2.77 points, to 1,396.07.