LONDON: England captain Harry Kane limped off injured early in the second half of the first leg of Tottenham's Champions League quarter-final against Manchester City on Tuesday, prompting fears his season could be over.

Kane appeared to roll his left ankle in a coming-together with City's Fabian Delph and was replaced by Lucas Moura in the 58th minute.

He was helped down the tunnel with the score still at 0-0.

Son Heung-min put Spurs ahead in the 78th minute.

Kane, who injured ligaments in his left ankle during Tottenham's Premier League defeat against Manchester United on January 13, only returned in late February, missing seven matches.

It was the third successive season the Spurs talisman has missed games due to an ankle injury.

The 25-year-old, the winner of the Golden Boot at last year's World Cup, has scored 27 goals for club and country this season.

His loss would be a huge blow for Spurs manager Mauricio Pochettino, whose side are currently fourth in the Premier League.

England boss Gareth Southgate will also be concerned, with the Nations League Finals looming.