Eurozone heavyweights Frankfurt and Paris were each down more than 1.5 percent, while London held up better thanks to a weak pound, as investors tracked ongoing Brexit turmoil.
On Wall Street, the Dow Jones index fell over 100 points at the opening bell.
"US stocks are lower in early action, with the technology sector being pressured by the potential fallout of the escalated trade tensions between the US and China," the Charles Schwab brokerage said in a note.
In the midst of a trade war with Beijing, President Donald Trump has barred US companies from engaging in telecommunications trade with foreign companies said to threaten American national security.
US internet giant Google, whose Android mobile operating system powers most of the world's smartphones, then announced that it was beginning to cut ties with China's Huawei, which Washington considers a national security threat.
- No quick fix -
================
"Equity markets are in the red... as dealers are still worried about the trade standoff between the US and China," said analyst David Madden at trading firm CMC Markets UK.
"The fact that Washington has effectively blocked Huawei from the US market is likely to drag out the trade dispute, and the prospect of a quick solution seems slim."
The move could have dramatic implications for Huawei smartphone users, as the Chinese telecoms giant will no longer have access to Google's proprietary services -- including Gmail and Google Maps apps -- a source close to the matter told AFP.
Reports also emerged Monday that several US chipmakers providing vital hardware for Huawei's smartphones have stopped supplying the Chinese firm.
SEB emerging markets strategist Per Hammarlund said that the latest development made it unlikely that Beijing and Washington would end their dispute in the runup to next month's G20 summit in Japan.
"Chances of a breakthrough before the G20 summit... are very small, with both sides likely reassessing their strategies following the failure to reach an agreement in Washington -- and the move by the US to blacklist Huawei," Hammarlund said.
- Sliver of hope -
==================
However, most Asian markets rose Monday after Trump showed signs of conciliation elsewhere.
Global markets have been in turmoil for two weeks since Trump threatened -- and later delivered -- a hike in tariffs on Chinese imports, to which Beijing retaliated and relit their debilitating trade battle.
The move also threw a spanner in the works for long-running negotiations between the economic superpowers that were thought to have been close to conclusion.
But there was a sliver of hope after Trump on Friday removed steel tariffs on Canada and Mexico and announced a six-month delay in imposing steep tariffs on auto imports as he seeks talks with Japan and the EU on the issue.
Meanwhile, Mumbai equities and the rupee soared on the back of exit polls suggesting business-friendly Prime Minister Narendra Modi was on course to be re-elected.
Sydney stocks and the Australian dollar rallied after a shock win for the conservatives, while Japanese dealers were cheered by forecast-beating GDP data.
However, the pound is wallowing near four-month lows on fears Britain will leave the European Union in October without a divorce deal.
- Key figures around 1330 GMT -
===============================
London - FTSE 100: DOWN 0.8 percent at 7,291.74 points
Frankfurt - DAX 30: DOWN 1.7 percent at 12,028.03
Paris - CAC 40: DOWN 1.7 percent at 5,344.58
EURO STOXX 50: DOWN 1.7 percent at 3,366.54
New York - Dow: DOWN 0.5 percent at 25,645.45
Tokyo - Nikkei 225: UP 0.2 percent at 21,301.73 (close)
Hong Kong - Hang Seng: DOWN 0.6 percent at 27,787.61 (close)
Shanghai - Composite: DOWN 0.4 percent at 2,870.60 (close)
Pound/dollar: UP at $1.2731 from $1.2724 at 2100 GMT
Euro/pound: DOWN at 87.65 pence from 87.72 pence
Euro/dollar: UP at $1.1160 from $1.1158
Dollar/yen: DOWN at 109.93 yen from 110.08 yen
Oil - Brent Crude: DOWN 15 cents at $72.06 per barrel
Oil - West Texas Intermediate: DOWN 28 cents at $62.64