Guterres "encourages all stakeholders to ensure the timely, inclusive, and transparent implementation of the agreement and resolve any outstanding issues through dialogue," said a UN statement.
The agreement was reached in the early hours Friday after two days of talks brokered by Ethiopian and African Union mediators.
It calls for setting up a sovereign council with a rotating military and civilian presidency for a period of three years and three months.
Guterres said he welcomed the parties' commitment to conduct an independent investigation of a June 3 crackdown on protesters in Khartoum that left dozens dead.
Sudan has been gripped by political deadlock since the generals ousted longtime president Omar al-Bashir in a palace coup in April following months of mass protests nationwide.