Deutsche's stock price has fallen 12 percent since Sunday's restructuring announcement to cut 18,000 jobs in a 7.4 billion euro ($8.29 billion) "reinvention". By 0842 GMT, the stock was down 5.2% on the day, their lowest for two weeks.
Analysts say Christian Sewing, CEO for just over a year, is right to slash Deutsche's trading desks but question if he can make the plan work in practice when interest rates are still low and U.S. banks have grown their share of the German market.
"Cutting back volatile, capital-intensive and underperforming sales and trading activities, and further reducing the cost base should improve profitability and strengthen leverage, but execution risks are high," rating agency Fitch said.
Last month, Fitch downgraded the bank to "BBB" status, the lowest investment-grade status.
Deutsche plans to focus on corporate banking and asset and wealth management, areas that can offer more stable revenues than investment banking but are increasingly competitive.
The bank began cutting jobs in its trading business on Monday, with staff laid off in offices stretching from Sydney to New York.