The Hang Seng Index fell 0.54 percent, or 155.85 points, to 28,463.77.
The benchmark Shanghai Composite Index dropped 0.38 percent, or 11.25 points, to 2,926.37 but the Shenzhen Composite Index, which tracks stocks on China's second exchange, edged up 0.08 percent, or 1.31 points, to 1,573.12.