After falling as much as 0.7pc during the session, the pan-European STOXX 600 index closed down 0.2pc, drawing support from a Bloomberg report that ECB staff were studying a potential change to the bank's inflation goal of near 2pc.
"The ECB changing its targets with regards to inflation could potentially enable it to be more accommodative for longer," said Craig Erlam, senior market analyst at OANDA in London.
Global stock markets have been recovering strongly from a sharp correction in May, helped by expectations that central banks will funnel more cash into the economy to counter a global slowdown driven by the US-China trade war.
But a combination of earnings worries, and some slightly stronger economic numbers which may prevent policymakers from acting, have weakened sentiment globally in the past week.
Shares in Europe's most valuable tech company fell 5.6pc after it said investors would have to wait till next year for a major improvement in margins as the business software group reported a 21pc fall in quarterly operating profit.
That drove Germany's DAX to a one-month low, while technology stocks dropped 1.5pc.
"We are not seeing the positive surprises (from earnings) that you would expect to see with the bar lowered, although it's a bit early to say that," said Erlam.
The Wall Street Journal reported overnight that progress toward a US-China trade deal had stalled while the Trump administration determines how to address Beijing's demands that it ease restrictions on Huawei Technologies.
That, along with some other disappointing earnings, including those for video streaming leader Netflix on Wednesday, drove a worsening of sentiment on both Wall Street and Asian markets.
London-listed stocks slid 0.5pc as the FTSE 100's internationally focused companies were hurt by gains for the pound on strong retail sales numbers and a vote by lawmakers to make a no-deal Brexit harder to achieve.
Another big decliner was Finland's Wartsila Oyj, which slumped 12pc after the engineering firm warned that it expected demand to weaken for its marine and energy businesses.
Italian banks bucked the gloomy trend, with a 0.4pc jump after comments from Deputy Prime Minister Luigi Di Maio about the future of a coalition government raised possibility of snap elections that could see a business-friendly centre-right coalition come to power.
Also limiting losses in Europe's blue-chip index was Swiss drugmaker Novartis, up 3pc after the company lifted full-year sales and profit targets.
British American Tobacco Plc shares jumped 5.5.pc, helped by strong quarterly results and a forecast from US tobacco company Philip Morris.