Southampton gained revenge for 9-0 thrashing at the hands of Leicester in October to continue their resurgence with a 2-1 win at the Foxes, while Chelsea and Manchester United secured comfortable wins in the race for the top-four on Saturday.
The Saints claimed their fifth win in six games at the King Power Stadium as they came from behind against the side second in the table.
Dennis Praet fired the hosts into an early lead, but Stuart Armstrong's deflected effort quickly pulled Ralph Hassenhuttl's men level.
Danny Ings then scored his 10th goal in 11 games eight minutes from time and the visitors survived a late scare when Jonny Evans's header was ruled out by VAR for offside.
Home comfort for Chelsea
Chelsea put their struggles at Stamford Bridge behind them with a 3-0 win over Burnley, who slide ever closer to the bottom three.
Jorginho opened the scoring from the penalty spot after Willian had been felled inside the area.
Tammy Abraham gave Frank Lampard's men breathing space before half-time as Nick Pope let his downward header through his grasp.
Callum Hudson-Odoi then scored his first Premier League goal by converting Cesar Azpilicueta's cross at the back post.
United ended a three-game winless run in style with Marcus Rashford and Anthony Martial once again leading the way for Ole Gunnar Solskjaer's men in a 4-0 rout of bottom-of-the-table Norwich.
Rashford marked his 200th appearance for the club with a brace as the England international opened the floodgates by meeting Juan Mata's perfectly measured cross at the back post.
Both Martial and Rashford had penalties saved by Tim Krul in United's 3-1 win at Carrow Road earlier this season, but this time the Dutchman was beaten by Rashford from the spot early in the second half.
Aubameyang sees red
Arsenal are now 11 points off the Champions League places as their revival under Mikel Arteta was halted by a red card for captain Pierre-Emerick Aubameyang in a 1-1 draw at Crystal Palace.
Aubameyang finished off a flowing move including Mesut Ozil and Alexandre Lacazette to give the Gunners a deserved first half lead.
Wolves bid for a return to European football next season is also faltering as they were held 1-1 at home by Newcastle.
Both goals came inside the first 14 minutes as Miguel Almiron fired the Magpies in front before Leander Dendoncker levelled for Wolves.
Everton bounced back from an embarrassing FA Cup exit to a much-changed and youthful Liverpool side last weekend thanks to a moment of magic from Richarlison to beat Brighton 1-0.