In a sign of the virus' expanding footprint, Brazil confirmed Latin America's first case, a 61-year-old who travelled to Italy's Lombardy region.
Greece also confirmed its first case Wednesday, a woman who had been in northern Italy, while Spain, Croatia, Austria, North Macedonia and Algeria have all reported cases linked to the country.
Several governments have advised against travel to Italy - which has 400 cases and 12 deaths - particularly to the outbreak epicentre in the north. 'No panic' Even as new cases continued to multiply beyond China's borders, the European Union sought to head off hysteria over the outbreak.
"This is a situation of concern, but we must not give in to panic," EU Health Commissioner Stella Kyriakides told reporters in Rome on Wednesday. "We must also be vigilant when it comes to misinformation and disinformation," she added.
The impact of the virus has moved beyond health systems.
Markets have wobbled in recent days - though Wall street stocks jumped back on Wednesday - while sports matches and festivals across Europe have been cancelled over virus fears.
A March 7 Six Nations rugby match between Italy and Ireland in Dublin was called off Wednesday, while the famed Venice Carnival was closed early over the weekend. As cases mounted across Europe, the WHO warned governments in Europe to remain vigilant. "You have to keep up and sustain these efforts so that no-one is left behind because ultimately health is a political choice," WHO Regional Director for Europe Hans Kluge said in Rome on Wednesday.
'Potential pandemic' The virus is believed to have emerged in a market in Wuhan city in China's Hubei province in late 2019, where it may have been transmitted to a human from an animal. China imposed extraordinary quarantine measures in several cities, locking in tens of millions of people as it sought to curb the virus' rapid spread.
The country announced Wednesday that people arriving in Beijing from other countries hit by the virus epidemic will go into 14-day self-quarantine. The WHO has praised Beijing for its response, though the communist government has faced criticism at home for silencing a whistleblowing doctor who has since died from the disease.
The WHO has called for countries to "prepare for a potential pandemic" - an epidemic that spreads throughout the world - even as new cases and deaths in China have continued to dip from previous numbers. It warned that poor countries are particularly at risk, sparking fears of how countries in Latin America and Africa would cope with potential outbreaks.
US accuses Iran In Asia, South Korea remains the worst-affected country after China, with the outbreak traced to a religious sect in the southern city of Daegu.
The city's streets have been largely deserted for days, apart from long queues at the few shops with masks for sale. South Korea reported 284 new infections Wednesday - its largest daily increase to date - taking the overall national tally to 1,261, with the death toll rising to 12.
A 23-year-old US soldier stationed at Camp Carroll in Daegu was also infected. Some 28,500 American troops are deployed in South Korea. Authorities urged the public to exercise extra caution, advising citizens to stay at home if they have a fever or respiratory symptoms. Meanwhile in the Middle East, Iran has emerged as a major hotspot, with a total of 139 cases and 19 deaths.
Even the country's deputy health minister Iraj Harirchi has contracted the virus. Iran's cyberpolice on Wednesday said 24 people were arrested for rumour-mongering about the outbreak. Authorities also announced domestic travel restrictions for confirmed or suspected cases instead of quarantining of whole cities.
Reporters Without Borders said Iran "seems to be concealing information about the epidemic in line with China's example", accusing it of also blocking independent reporting of the outbreak. Several Gulf countries have announced measures to cut links with Iran in an attempt to stop the virus spread. In the US, health authorities have warned the virus is likely to spread on its soil, while President Donald Trump will hold a news conference on the virus later Wednesday in Washington.