Sunak said he was ready to increase the size of the loan guarantees - already equivalent to 15% of Britain's annual economic output - to ensure cash gets to all companies needing it as their businesses slump.
Other measures announced on Tuesday included extending the recent suspension of a property tax paid by small companies to all businesses in the retail, hospitality and leisure sectors.
Those companies would also get cash grants as part of a 20 billion-pound increase in direct support for companies, on top of help announced last week, and the government would discuss a support package for airlines and airports, Sunak said.
Johnson on Monday told people to avoid pubs, clubs, restaurants, cinemas and theatres, leaving many companies in those sectors facing the prospect of collapse. The virus crisis has also had a major hit to the aviation industry.
Britain's biggest airports including Heathrow and Gatwick have asked Johnson to be included in any support for the aviation industry, saying they face the threat of a complete shutdown without it.
Banks and lenders would offer a three-month mortgage holiday for those in difficulty, Sunak said.
"UNIMAGINABLE SCALE"
"This struggle will not be overcome by a single package of measures or isolated interventions," he said. "This national effort will be underpinned by government interventions in the economy on a scale unimaginable only a few weeks ago."
The Bank of England said it would set up a new fund with the finance ministry to buy commercial debt of up to one-year in duration issued by companies making a "material contribution" to Britain's economy.
It added that the fund would be financed out of the creation of central bank reserves - in other words with new money, much like the BoE's quantitative easing programme.
Earlier on Tuesday, Britain's budget forecasters said the scale of the borrowing needed to fight the coronavirus hit to the economy might resemble the country's immense debt splurge during World War Two.
"Now is not a time to be squeamish about public sector debt," Robert Chote, head of the Office for Budget Responsibility, told lawmakers. "We ran during the Second World War budget deficits in excess of 20% of GDP five years on the trot and that was the right thing to do."
On Monday, French President Emmanuel Macron said his government would guarantee 300 billion euros worth of loans, and promised that no French company would be allowed to collapse.
New Bank of England Governor Andrew Bailey promised "prompt action" on Monday, less than a week after an emergency rate cut by the BoE which took its benchmark rate to just 0.25%. Investors are watching for another rate cut, possibly before the BoE's next scheduled announcement on March 26. The central bank is also expected to expand its 435 billion-pound government bond buying programme.