"The drone fired two missiles on a house in Hassokhel town," 25 kilometres east of Miranshah, the main town in North Waziristan, a security official said.

"So far five bodies have been recovered from the compound, which is ringed by militants."

Two other officials confirmed the attack, saying the casualties may go up.

Thursday's drone strike came after one on Wednesday that killed four militants in the same region, and followed a summit of NATO alliance leaders in Chicago earlier this week.

Pakistan says the missile attacks are counter-productive, violate its sovereignty, kill civilians and fuel anti-US sentiment.