According to a preliminary flash estimate from the European Union's statistics office Eurostat, economic output in the 19 countries sharing the euro currency in January-March was 3.8% smaller than in the previous three months - the sharpest quarterly decline since the time series started in 1995.
Economists polled by Reuters had expected a 3.5% contraction after a 0.1% quarterly growth in the last three months of 2019.
Year-on-year the gross domestic product contraction was 3.3% in the first quarter. However, coronavirus-related lockdowns were only in place for two to three weeks of the quarter.
Economists noted that in several countries that reported first quarter GDP numbers, the depth of the recession was linked to the severity of national lockdowns. France's GDP fell 5.8%, Spain's by 5.2%, Belgium's by 3.9% and Austria's by 2.5%.
Eurostat also said consumer prices in the euro zone grew 0.3% month-on-month in April for a 0.4% year-on-year increase, slowing from 0.7% year-on-year in March.
But the slowdown of inflation was smaller than expected by economists, who on average forecast a deceleration to 0.1% year-on-year in Aril, according to a Reuters poll.
The biggest drag on the overall index cam from energy prices, which dropped 9.6% year-on-year.
Without the volatile energy and unprocessed food components - what the European Central Bank calls core inflation - prices grew 0.7% on the month for a 1.1% year-on-year increase. In March this measures was an increase of 1.2% percent.
An even narrower measure of inflation that also excludes alcohol and tobacco prices and is followed by many market economists showed prices going up 0.8% on the month in April and 0.9% year-on-year, against a 1.0% annual increase in March.
Eurostat said euro zone unemployment, a lagging indicator that reflects changes in the economy with a delay, ticked up to 7.4% of the workforce in March from 7.3% in February.
Economists said they expected that number to increase in the coming months, despite a European Union scheme to help subsidise wages across the 27-nation bloc so that employers cut working hours rather than jobs.