As France and Spain embraced new freedoms and Britain plotted a path to normality, the Chinese city of Wuhan where the pandemic was born reported a second day of new cases after a month without a sign of the virus.
And neighbouring South Korea announced its highest number of infections for more than a month driven by a cluster in a Seoul nightlife district.
With millions out of work and economies badly bruised, governments are desperate to hit the accelerator, but most are choosing a gradual approach as fears about a resurgence of the virus loom large.
In parts of Europe, officials have been emboldened by declining death rates, with France's daily toll dropping to 70 on Sunday - its lowest since early April - and Spain's daily fatalities falling below 200.
The French were able venture outdoors without filling in a permit for the first time in nearly eight weeks on Monday, and some shops reopened their doors. The wide boulevards of the Champs-Elysees in Paris were once again back to life with cars and shoppers waiting patiently to make purchases, but things were not as before. "It's a little unreal, everyone is wearing masks, it's really strange," said Irina, queuing outside a cosmetics store.
Many Spaniards revelled in being able to visit outdoor terraces and cafes again after months under one of the world's toughest lockdowns, although virus hotspots such as Madrid and Barcelona remain under wraps.
Shopping strips were once again populated in Greece, while in other parts of Europe from the Netherlands to Switzerland and Croatia youngsters headed back to the classroom after weeks at home.
Germany too has set in motion the reopening of shops, eateries, schools and gyms, but Chancellor Angela Merkel refreshed warnings to stay safe after official data showed the infection rate picking up speed again.
Russia took a similarly cautious approach and said some work could resume this week, even as daily cases hit over 11,000, a record high in the country, and deaths topped 2,000.
With governments across the world trying to avoid a second wave, Asian nations that were among the first engulfed by the virus but have since brought it to heel are being keenly watched.
South Korean officials ordered nightclubs and bars closed after a new cluster of at least 86 cases linked to an entertainment district in the capital - many in gay clubs.
Officials scrambled to trace thousands of people who visited the area, but efforts were hampered with many believed to be reluctant to come forward because of the stigma surrounding homosexuality.
New Zealand, meanwhile, will phase out its lockdown over the next 10 days, although some restrictions will remain.
Prime Minister Jacinda Ardern warned in a televised address that "none of us can assume COVID is not with us", but said the country had only 90 active cases after a seven-week lockdown.