Bangladesh was hit on Saturday by the fourth opposition-led general strike this month, but the prime minister said the protests would never achieve their aim of forcing her to quit.
The strike closed businesses and disrupted transport nation-wide, despite complaints that such campaigns were causing serious economic losses for the already impoverished country.
"We will not step down a single day before our term ends. If the opposition wants to force us out by calling strikes, they are pursuing an unachievable mission," Prime minister Begum Khaleda Zia told a rally in Dhaka.
The next elections are not due before October 2006.
More than 50 people were injured in strike-related clashes outside the capital, local officials said. As in previous strikes, police drove away hundreds of strike supporters gathering on Dhaka's streets.
Police detained about 70 activists, including women, in the city, mostly from outside the central office of the main opposition party, the Awami League, which sponsored the strikes, witnesses said.
About 50 other people were detained in Chittagong port city, local reporters said. Police said the strike ended mostly peacefully.
Officials said Saturday's strike lost some of its steam after authorities ordered police to act firmly to control unruly mobs and resist any major showdown by the opposition.
The Awami League and its supporters have launched the series of strikes to campaign against what they say is sweeping corruption, political repression, deteriorating law and order and rising prices.
Awami chief Sheikh Hasina said on Friday she would call for more strikes unless Khaleda, about half way through her five-year term, called early elections.
General strikes and street disturbances are common in Bangladesh but no governments have been toppled by such protests since 1990.
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