Japanese scientists said Wednesday they had developed a surgical 'nano-sheet' one thousand times thinner than Cellophane that can patch up internal wounds and later dissolves inside the body. The transparent and adhesive sheeting, made from a substance derived from crab shells and a viscous gum from algae, is just 75 nanometres thick. A nanometre is one-billionth of one metre.
"This is the world's thinnest adhesive plaster," said Toshinori Fujie, a researcher involved in the joint project by Tokyo's private Waseda University and the National Defence Medical College. "We know food Cellophane clings on to the surface of various objects. We have made a sheet ultimately thin... so that it is highly flexible and can stick to organs well with no glue," he told AFP.
Surgeons normally stitch or staple wounds, or they use sheets several millimetres thick coated with fibrin, a protein that makes blood clot and works like glue but which can cause unwanted sticking to nearby tissue. In an experiment repeated several times, the team placed a square piece of the new nano-sheet onto a six-millimetre-wide hole in a dog's lung.
The sheet was strong enough to withstand the pressure of the dog's breathing and helped the wounds heal within one month, leaving no visible trace, Fujie said. Researchers hope to launch human clinical trials in three years. They may also expand the use of the sheets for external use.
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