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NEW YORK: US stocks ended sharply higher on Wednesday, with the S&P 500 at its highest since early June, following promising early data for a potential Covid-19 vaccine and a strong quarterly report from Goldman Sachs. Moderna Inc rallied 6.9% after a small-scale study showed its experimental Covid-19 vaccine produced high levels of virus-killing antibodies.

Travel-related stocks Carnival Corp, Royal Caribbean Cruises Ltd, Marriott International and Wynn Resorts surged between 7% and 21%, and the S&P 1500 airlines index rallied over 10%.

The S&P 500 beat the technology-heavy Nasdaq Composite for a fourth straight session, a feat scored only twice since Wall Street launched its massive recovery last March.

Gains for the Nasdaq were capped by online retail giant Amazon.com Inc, video streaming platform Netflix Inc and Microsoft Corp, which slipped after surging to record highs recently.

"The Moderna news woke everybody up again that this is not going to last forever, and there is light at the end of the tunnel. That is why you are seeing such a strong move today into those economically sensitive stocks," said Tim Ghriskey, Chief Investment Strategist Inverness Counsel in New York.

Adding to investors' enthusiasm, the Federal Reserve's Beige Book survey showed US businesses saw an uptick in activity into the beginning of July as states eased restrictions to contain the novel coronavirus pandemic.

Near the end of the trading session, US President Donald Trump said his administration had completed a top to bottom overhaul of the infrastructure approval process.

The Dow Jones Industrial Average rose 0.85% to end at 26,870.03 points, while the S&P 500 gained 0.91% to 3,226.55.

The Nasdaq Composite climbed 0.59% to 10,550.49.

Goldman Sachs rose 1.4% after it said its trading revenue doubled in the second quarter, driven by big swings in stock and bond markets since March.

Morgan Stanley and Bank of America gained nearly 2% ahead of their results on Thursday. The broader banking index climbed 2.9%.

UnitedHealth Group Inc fell 1.4% after warning of rising costs later this year as Americans catch up on less urgent surgeries halted by the coronavirus pandemic.

Advancing issues outnumbered declining ones on the NYSE by a 5.23-to-1 ratio; on Nasdaq, a 4.31-to-1 ratio favoured advancers.

The S&P 500 posted 31 new 52-week highs and no new lows; the Nasdaq Composite recorded 78 new highs and three new lows.

Volume on US exchanges was 11.0 billion shares, compared with the 11.7 billion average for the full session over the last 20 trading days.

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