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An assailant has stabbed to death the son of former German president Richard von Weizsaecker in an attack at a Berlin hospital that left one other person seriously injured, police said Wednesday.

Fritz von Weizsaecker, a doctor, had just delivered a lecture on liver diseases at the Schlosspark hospital in the west Berlin neighbourhood of Charlottenburg on Tuesday evening when he was stabbed in the neck.

The 59-year-old, a father of four, died at the scene despite efforts to save him.

His assailant was overpowered by other people present, one of whom was severely injured in the process.

Prosecutors said the 57-year-old attacker had bought the knife in his home state of Rhineland-Palatinate in the far west of Germany and travelled to Berlin by train. They said he had been diagnosed with an "acute mental illness" and had a "probably delusional general dislike" of the Weizsaecker family.

Copyright Agence France-Presse, 2019

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