The rising hostilities underscore a dangerous intensification of Yemen's conflict between the coalition-backed Yemeni government and the Iran-backed Huthis, despite a renewed US push to end the war in the crude-rich region.
The Saudi-led coalition intervened in Yemen in March 2015 after the Houthis ousted the internationally recognised government from power in the capital, Sanaa.
The bomb-laden unmanned aerial vehicle aimed to target "civilians and civilian objects", coalition spokesman Colonel Turki al-Malki said in a statement carried on Saudi state media.
Israel has carried out hundreds of air and missile strikes on Syria since civil war broke out in 2011, targeting Iranian and Lebanese Hezbollah forces as well as Syrian government troops.
Saudi Arabia is stuck in a military quagmire in Yemen, which has been locked in conflict since the rebels took control of the capital Sanaa in 2014 and went on to seize much of the north.
Additionally, three Haitians -- one a gang leader and two who were government officials at the time -- accused of responsibility for the November 2018 La Saline attack that left 71 people dead were also named for sanctions.